Beta-amyloid Deposition in Biliary Atresia Reduces Liver Regeneration by Inhibiting Energy Metabolism and Mammalian Target of Rapamycin Signaling

INTRODUCTION: Biliary atresia (BA) is a devastating obstructive bile duct disease found in newborns. This study aims to investigate the roles and involved mechanisms of beta-amyloid (Aβ) in the pathogenesis of BA. METHODS: We examined the distribution of Aβ protein and its precursor in the livers of...

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Detalles Bibliográficos
Autores principales: Tian, Xinbei, Wang, Ying, Zhou, Ying, Wu, Bo, Lu, Ying, Du, Jun, Wang, Weipeng, Cai, Wei, Xiao, Yongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476755/
https://www.ncbi.nlm.nih.gov/pubmed/36137184
http://dx.doi.org/10.14309/ctg.0000000000000536

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