Impact of a pyridazine derivative on tripartite synapse ultrastructure in hippocampus: a three-dimensional analysis

INTRODUCTION: We previously discovered a pyridazine derivative compound series that can improve cognitive functions in mouse models of Alzheimer’s disease. One of the advanced compounds from this series, LDN/OSU-0215111-M3, was selected as the preclinical development candidate. This compound activat...

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Detalles Bibliográficos
Autores principales: Xu, Zan, Foster, Joshua B., Lashley, Rashelle, Wang, Xueqin, Benson, Emily, Kidd, Grahame, Lin, Chien-liang Glenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476950/
https://www.ncbi.nlm.nih.gov/pubmed/37671169
http://dx.doi.org/10.3389/fncel.2023.1229731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476950/
https://www.ncbi.nlm.nih.gov/pubmed/37671169
http://dx.doi.org/10.3389/fncel.2023.1229731

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