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Impact of a pyridazine derivative on tripartite synapse ultrastructure in hippocampus: a three-dimensional analysis
INTRODUCTION: We previously discovered a pyridazine derivative compound series that can improve cognitive functions in mouse models of Alzheimer’s disease. One of the advanced compounds from this series, LDN/OSU-0215111-M3, was selected as the preclinical development candidate. This compound activat...
Autores principales: | Xu, Zan, Foster, Joshua B., Lashley, Rashelle, Wang, Xueqin, Benson, Emily, Kidd, Grahame, Lin, Chien-liang Glenn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10476950/ https://www.ncbi.nlm.nih.gov/pubmed/37671169 http://dx.doi.org/10.3389/fncel.2023.1229731 |
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