Olanzapine Overdose in a Two-Year-Old Girl Resulting in Both High Serum and Plasma Levels

The antipsychotic olanzapine is used increasingly to treat various psychiatric illnesses. Accidental olanzapine overdose is uncommon among children. Here, we report a case of a child presenting with an unexplained coma. Accidental ingestion of olanzapine (20 mg) was confirmed by measurement of drug...

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Detalles Bibliográficos
Autores principales: Yokoyama, Koji, Yakuo, Toshinari, Mamada, Mitsukazu, Nagata, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Emergency Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477032/
https://www.ncbi.nlm.nih.gov/pubmed/37671213
http://dx.doi.org/10.7759/cureus.43002
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author Yokoyama, Koji
Yakuo, Toshinari
Mamada, Mitsukazu
Nagata, Masashi
author_facet Yokoyama, Koji
Yakuo, Toshinari
Mamada, Mitsukazu
Nagata, Masashi
author_sort Yokoyama, Koji
collection PubMed
description The antipsychotic olanzapine is used increasingly to treat various psychiatric illnesses. Accidental olanzapine overdose is uncommon among children. Here, we report a case of a child presenting with an unexplained coma. Accidental ingestion of olanzapine (20 mg) was confirmed by measurement of drug concentrations in both serum and plasma.
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spelling pubmed-104770322023-09-05 Olanzapine Overdose in a Two-Year-Old Girl Resulting in Both High Serum and Plasma Levels Yokoyama, Koji Yakuo, Toshinari Mamada, Mitsukazu Nagata, Masashi Cureus Emergency Medicine The antipsychotic olanzapine is used increasingly to treat various psychiatric illnesses. Accidental olanzapine overdose is uncommon among children. Here, we report a case of a child presenting with an unexplained coma. Accidental ingestion of olanzapine (20 mg) was confirmed by measurement of drug concentrations in both serum and plasma. Cureus 2023-08-05 /pmc/articles/PMC10477032/ /pubmed/37671213 http://dx.doi.org/10.7759/cureus.43002 Text en Copyright © 2023, Yokoyama et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Yokoyama, Koji
Yakuo, Toshinari
Mamada, Mitsukazu
Nagata, Masashi
Olanzapine Overdose in a Two-Year-Old Girl Resulting in Both High Serum and Plasma Levels
title Olanzapine Overdose in a Two-Year-Old Girl Resulting in Both High Serum and Plasma Levels
title_full Olanzapine Overdose in a Two-Year-Old Girl Resulting in Both High Serum and Plasma Levels
title_fullStr Olanzapine Overdose in a Two-Year-Old Girl Resulting in Both High Serum and Plasma Levels
title_full_unstemmed Olanzapine Overdose in a Two-Year-Old Girl Resulting in Both High Serum and Plasma Levels
title_short Olanzapine Overdose in a Two-Year-Old Girl Resulting in Both High Serum and Plasma Levels
title_sort olanzapine overdose in a two-year-old girl resulting in both high serum and plasma levels
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477032/
https://www.ncbi.nlm.nih.gov/pubmed/37671213
http://dx.doi.org/10.7759/cureus.43002
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AT mamadamitsukazu olanzapineoverdoseinatwoyearoldgirlresultinginbothhighserumandplasmalevels
AT nagatamasashi olanzapineoverdoseinatwoyearoldgirlresultinginbothhighserumandplasmalevels

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