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Characterization of an in vitro steatosis model simulating activated de novo lipogenesis in MAFLD patients

Activated de novo lipogenesis (DNL) is the critical pathway involved in the progression of metabolic-associated fatty liver disease (MAFLD). We present an in vitro steatosis model for MAFLD that induces steatosis through activated DNL. This model utilizes insulin and LXR receptor ligand T0901317, el...

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Detalles Bibliográficos
Autores principales:	Kim, Woonghee, Li, Mengzhen, Jin, Han, Yang, Hong, Türkez, Hasan, Uhlén, Mathias, Zhang, Cheng, Mardinoglu, Adil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477067/ https://www.ncbi.nlm.nih.gov/pubmed/37674987 http://dx.doi.org/10.1016/j.isci.2023.107727

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