Inhibiting PI3K/Akt-Signaling Pathway Improves Neurobehavior Changes in Anti-NMDAR Encephalitis Mice by Ameliorating Blood–Brain Barrier Disruption and Neuronal Damage

The disruption of the blood–brain barrier (BBB) is hypothesized to be involved in the progression of anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis, but its mechanism is still unclear. Recently, the phosphatidylinositol 3-kinase (PI3K)/threonine kinase (Akt) pathway is involved in the regul...

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Detalles Bibliográficos
Autores principales: Gong, Zhuowei, Lao, Dayuan, Wu, Yu, Li, Taiyan, Lv, Sirao, Mo, Xuean, Huang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477152/
https://www.ncbi.nlm.nih.gov/pubmed/37314618
http://dx.doi.org/10.1007/s10571-023-01371-3

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