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Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion

The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (T(ex)) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion withou...

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Autores principales: Potolitsyna, Natalya, Parshukova, Olga, Vakhnina, Nadezhda, Alisultanova, Nadezhda, Kalikova, Lubov, Tretyakova, Anastasia, Chernykh, Alexey, Shadrina, Vera, Duryagina, Arina, Bojko, Evgeny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477198/
https://www.ncbi.nlm.nih.gov/pubmed/37667373
http://dx.doi.org/10.14814/phy2.15801
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author Potolitsyna, Natalya
Parshukova, Olga
Vakhnina, Nadezhda
Alisultanova, Nadezhda
Kalikova, Lubov
Tretyakova, Anastasia
Chernykh, Alexey
Shadrina, Vera
Duryagina, Arina
Bojko, Evgeny
author_facet Potolitsyna, Natalya
Parshukova, Olga
Vakhnina, Nadezhda
Alisultanova, Nadezhda
Kalikova, Lubov
Tretyakova, Anastasia
Chernykh, Alexey
Shadrina, Vera
Duryagina, Arina
Bojko, Evgeny
author_sort Potolitsyna, Natalya
collection PubMed
description The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (T(ex)) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion without a load or with a load of 2%–10% of body weight (BW). In the first group, we established that for untrained rats, the load of 4% BW in the swimming to exhaustion test was optimal for endurance assessment in comparison with other loads. The second group of rats went through a preliminary test with swimming to exhaustion at 4% BW and was then divided into two subgroups: long swimming time (LST, T(ex) > 240 min) and short swimming time (SST, T(ex) < 90 min). All rats of the second group performed, for 6 days, an experimental training protocol: swimming for 20 min each day with weight increasing each day. We established that the AT was 3% BW in SST rats and 5% BW in LST rats. The AT shifted to the right on the lactate curve in LST rats. Also, at the AT in the LST rats, we found significantly lower levels of blood lactate, cortisol, and NO.
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spelling pubmed-104771982023-09-06 Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion Potolitsyna, Natalya Parshukova, Olga Vakhnina, Nadezhda Alisultanova, Nadezhda Kalikova, Lubov Tretyakova, Anastasia Chernykh, Alexey Shadrina, Vera Duryagina, Arina Bojko, Evgeny Physiol Rep Original Articles The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (T(ex)) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion without a load or with a load of 2%–10% of body weight (BW). In the first group, we established that for untrained rats, the load of 4% BW in the swimming to exhaustion test was optimal for endurance assessment in comparison with other loads. The second group of rats went through a preliminary test with swimming to exhaustion at 4% BW and was then divided into two subgroups: long swimming time (LST, T(ex) > 240 min) and short swimming time (SST, T(ex) < 90 min). All rats of the second group performed, for 6 days, an experimental training protocol: swimming for 20 min each day with weight increasing each day. We established that the AT was 3% BW in SST rats and 5% BW in LST rats. The AT shifted to the right on the lactate curve in LST rats. Also, at the AT in the LST rats, we found significantly lower levels of blood lactate, cortisol, and NO. John Wiley and Sons Inc. 2023-09-04 /pmc/articles/PMC10477198/ /pubmed/37667373 http://dx.doi.org/10.14814/phy2.15801 Text en © 2023 Institute of Physiology of Komi Science Center of the UB of the RAS. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Potolitsyna, Natalya
Parshukova, Olga
Vakhnina, Nadezhda
Alisultanova, Nadezhda
Kalikova, Lubov
Tretyakova, Anastasia
Chernykh, Alexey
Shadrina, Vera
Duryagina, Arina
Bojko, Evgeny
Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion
title Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion
title_full Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion
title_fullStr Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion
title_full_unstemmed Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion
title_short Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion
title_sort lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477198/
https://www.ncbi.nlm.nih.gov/pubmed/37667373
http://dx.doi.org/10.14814/phy2.15801
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