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Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion
The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (T(ex)) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion withou...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477198/ https://www.ncbi.nlm.nih.gov/pubmed/37667373 http://dx.doi.org/10.14814/phy2.15801 |
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author | Potolitsyna, Natalya Parshukova, Olga Vakhnina, Nadezhda Alisultanova, Nadezhda Kalikova, Lubov Tretyakova, Anastasia Chernykh, Alexey Shadrina, Vera Duryagina, Arina Bojko, Evgeny |
author_facet | Potolitsyna, Natalya Parshukova, Olga Vakhnina, Nadezhda Alisultanova, Nadezhda Kalikova, Lubov Tretyakova, Anastasia Chernykh, Alexey Shadrina, Vera Duryagina, Arina Bojko, Evgeny |
author_sort | Potolitsyna, Natalya |
collection | PubMed |
description | The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (T(ex)) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion without a load or with a load of 2%–10% of body weight (BW). In the first group, we established that for untrained rats, the load of 4% BW in the swimming to exhaustion test was optimal for endurance assessment in comparison with other loads. The second group of rats went through a preliminary test with swimming to exhaustion at 4% BW and was then divided into two subgroups: long swimming time (LST, T(ex) > 240 min) and short swimming time (SST, T(ex) < 90 min). All rats of the second group performed, for 6 days, an experimental training protocol: swimming for 20 min each day with weight increasing each day. We established that the AT was 3% BW in SST rats and 5% BW in LST rats. The AT shifted to the right on the lactate curve in LST rats. Also, at the AT in the LST rats, we found significantly lower levels of blood lactate, cortisol, and NO. |
format | Online Article Text |
id | pubmed-10477198 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104771982023-09-06 Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion Potolitsyna, Natalya Parshukova, Olga Vakhnina, Nadezhda Alisultanova, Nadezhda Kalikova, Lubov Tretyakova, Anastasia Chernykh, Alexey Shadrina, Vera Duryagina, Arina Bojko, Evgeny Physiol Rep Original Articles The present study assessed a complex of biochemical parameters at the anaerobic threshold (AT) in untrained male Wistar rats with different times to exhaustion (T(ex)) from swimming. The first group of rats was randomly divided into six subgroups and subjected to a swimming test to exhaustion without a load or with a load of 2%–10% of body weight (BW). In the first group, we established that for untrained rats, the load of 4% BW in the swimming to exhaustion test was optimal for endurance assessment in comparison with other loads. The second group of rats went through a preliminary test with swimming to exhaustion at 4% BW and was then divided into two subgroups: long swimming time (LST, T(ex) > 240 min) and short swimming time (SST, T(ex) < 90 min). All rats of the second group performed, for 6 days, an experimental training protocol: swimming for 20 min each day with weight increasing each day. We established that the AT was 3% BW in SST rats and 5% BW in LST rats. The AT shifted to the right on the lactate curve in LST rats. Also, at the AT in the LST rats, we found significantly lower levels of blood lactate, cortisol, and NO. John Wiley and Sons Inc. 2023-09-04 /pmc/articles/PMC10477198/ /pubmed/37667373 http://dx.doi.org/10.14814/phy2.15801 Text en © 2023 Institute of Physiology of Komi Science Center of the UB of the RAS. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Potolitsyna, Natalya Parshukova, Olga Vakhnina, Nadezhda Alisultanova, Nadezhda Kalikova, Lubov Tretyakova, Anastasia Chernykh, Alexey Shadrina, Vera Duryagina, Arina Bojko, Evgeny Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion |
title | Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion |
title_full | Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion |
title_fullStr | Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion |
title_full_unstemmed | Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion |
title_short | Lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion |
title_sort | lactate thresholds and role of nitric oxide in male rats performing a test with forced swimming to exhaustion |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477198/ https://www.ncbi.nlm.nih.gov/pubmed/37667373 http://dx.doi.org/10.14814/phy2.15801 |
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