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A hybrid in silico/in-cell controller for microbial bioprocesses with process-model mismatch

Bioprocess optimization using mathematical models is prevalent, yet the discrepancy between model predictions and actual processes, known as process-model mismatch (PMM), remains a significant challenge. This study proposes a novel hybrid control system called the hybrid in silico/in-cell controller...

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Detalles Bibliográficos
Autores principales: Ohkubo, Tomoki, Soma, Yuki, Sakumura, Yuichi, Hanai, Taizo, Kunida, Katsuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477343/
https://www.ncbi.nlm.nih.gov/pubmed/37666852
http://dx.doi.org/10.1038/s41598-023-40469-y