The arginine methyltransferase PRMT5 promotes mucosal defense in the intestine

PRMT5 is a type II arginine methyltransferase abundantly expressed in the colonic epithelium. It is up-regulated in inflammatory bowel disease and colorectal cancer. However, its role in mucosal defense against enteric infection has not been studied. Here, we report that Prmt5 in the murine colon is...

Descripción completa

Detalles Bibliográficos
Autores principales: Hernandez, Juan E, Llorente, Cristina, Ma, Shengyun, Miyamoto, Kiana T, Sinha, Saptarshi, Steele, Scarlet, Xiao, Zihui, Lai, Ching-Jung, Zuniga, Elina I, Ghosh, Pradipta, Schnabl, Bernd, Huang, Wendy Jia Men
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477432/
https://www.ncbi.nlm.nih.gov/pubmed/37666668
http://dx.doi.org/10.26508/lsa.202302026

Ejemplares similares

Ejemplares similares