Chlorotoxin binds to both matrix metalloproteinase 2 and neuropilin 1

Chlorotoxin (CTX), a scorpion venom–derived 36-residue miniprotein, binds to and is taken up selectively by glioblastoma cells. Previous studies provided controversial results concerning target protein(s) of CTX. These included CLC3 chloride channel, matrix metalloproteinase 2 (MMP-2), regulators of...

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Detalles Bibliográficos
Autores principales: Farkas, Sándor, Cioca, Daniel, Murányi, József, Hornyák, Péter, Brunyánszki, Attila, Szekér, Patrik, Boros, Eszter, Horváth, Patrik, Hujber, Zoltán, Rácz, Gábor Z., Nagy, Noémi, Tóth, Rebeka, Nyitray, László, Péterfi, Zalán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477481/
https://www.ncbi.nlm.nih.gov/pubmed/37394009
http://dx.doi.org/10.1016/j.jbc.2023.104998

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