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Immune landscape and regulatory mechanisms in human atherosclerotic coronary plaques: Evidence from single-cell and bulk transcriptomics

Atherosclerosis is a chronic immuno-inflammatory disease, however, the immune landscape and regulatory mechanisms have not been clear. We detected seven principal immune cell clusters with distinct phenotypic and spatial characteristics using single-cell RNA-sequencing of aortic immune cells from pa...

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Detalles Bibliográficos
Autores principales: Liang, Wei-Lin, Liao, Hui-Ling, Liang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477495/
https://www.ncbi.nlm.nih.gov/pubmed/37674826
http://dx.doi.org/10.1016/j.heliyon.2023.e19392

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