Loss of hepatic FTCD promotes lipid accumulation and hepatocarcinogenesis by upregulating PPARγ and SREBP2

BACKGROUND & AIMS: Exploiting key regulators responsible for hepatocarcinogenesis is of great importance for the prevention and treatment of hepatocellular carcinoma (HCC). However, the key players contributing to hepatocarcinogenesis remain poorly understood. We explored the molecular mechanism...

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Detalles Bibliográficos
Autores principales: Wang, Siying, Zhou, Yangyang, Yu, Ruobing, Ling, Jing, Li, Botai, Yang, Chen, Cheng, Zhuoan, Qian, Ruolan, Lin, Zhang, Yu, Chengtao, Zheng, Jiaojiao, Zheng, Xingling, Jia, Qi, Wu, Wei, Wu, Qiangxin, Chen, Mengnuo, Yuan, Shengxian, Dong, Wei, Shi, Yaoping, Jansen, Robin, Hao, Yujun, Yao, Ming, Qin, Wenxin, Jin, Haojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477690/
https://www.ncbi.nlm.nih.gov/pubmed/37675273
http://dx.doi.org/10.1016/j.jhepr.2023.100843

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