Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody

Phosphatase of regenerating liver 3 (PRL3) is a specific tumor antigen overexpressed in a broad range of adult cancer types. However, its physiological expression in pediatric embryonal and mesenchymal tumors and its association with clinical outcomes in children is unknown. We sought to profile the...

Descripción completa

Detalles Bibliográficos
Autores principales: Loh, Amos Hong Pheng, Thura, Min, Gupta, Abhishek, Tan, Sheng Hui, Kuan, Kelvin Kam Yew, Ang, Koon Hwee, Merchant, Khurshid, Chang, Kenneth Tou En, Yon, Hui Yi, Chen, Yong, Cheng, Mathew Hern Wang, Mahadev, Arjandas, Ng, Matthew Chau Hsien, Seng, Michaela Su-Fern, Iyer, Prasad, Chia, Pei Ling, Soh, Shui Yen, Zeng, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477756/
https://www.ncbi.nlm.nih.gov/pubmed/37674627
http://dx.doi.org/10.1016/j.omto.2023.08.006

Ejemplares similares

Ejemplares similares