Cargando…
Insights into the function of HDAC3 and NCoR1/NCoR2 co-repressor complex in metabolic diseases
Histone deacetylase 3 (HDAC3) and nuclear receptor co-repressor (NCoR1/2) are epigenetic regulators that play a key role in gene expression and metabolism. HDAC3 is a class I histone deacetylase that functions as a transcriptional co-repressor, modulating gene expression by removing acetyl groups fr...
Autores principales: | Paluvai, Harikrishnareddy, Shanmukha, Kumar D., Tyedmers, Jens, Backs, Johannes |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477789/ https://www.ncbi.nlm.nih.gov/pubmed/37674539 http://dx.doi.org/10.3389/fmolb.2023.1190094 |
Ejemplares similares
-
Evolution of NCoR-1 and NCoR-2 corepressor alternative mRNA splicing in placental mammals
por: Privalsky, Martin L., et al.
Publicado: (2019) -
NCoR controls glioblastoma tumor cell characteristics
por: Heldring, Nina, et al.
Publicado: (2014) -
Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex
por: Hudson, Gregg M., et al.
Publicado: (2015) -
Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERBβ
por: Mosure, Sarah A., et al.
Publicado: (2021) -
Autophagy regulates lipid metabolism through selective turnover of NCoR1
por: Saito, Tetsuya, et al.
Publicado: (2019)