Liver‐Inspired Polyetherketoneketone Scaffolds Simulate Regenerative Signals and Mobilize Anti‐Inflammatory Reserves to Reprogram Macrophage Metabolism for Boosted Osteoporotic Osseointegration (Adv. Sci. 25/2023)

Liver‐Inspired Polyetherketoneketone Scaffolds In article number 2302136, Hao Gu, Jin Wen, Xinquan Jiang, and co‐workers are inspired from the liver extracellular skeleton morphology and develop a biomimetic scaffold. The scaffold reproduces an identical bio‐signal derived from the bio‐template in m...

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Detalles Bibliográficos
Autores principales: Gu, Hao, Zhu, Yuhui, Yang, Jiawei, Jiang, Ruixue, Deng, Yuwei, Li, Anshuo, Fang, Yingjing, Wu, Qianju, Tu, Honghuan, Chang, Haishuang, Wen, Jin, Jiang, Xinquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477849/
http://dx.doi.org/10.1002/advs.202370166
Descripción
Sumario:Liver‐Inspired Polyetherketoneketone Scaffolds In article number 2302136, Hao Gu, Jin Wen, Xinquan Jiang, and co‐workers are inspired from the liver extracellular skeleton morphology and develop a biomimetic scaffold. The scaffold reproduces an identical bio‐signal derived from the bio‐template in macrophages and causes retrograde translocation of arginase‐2 in mitochondria, optimizing osseointegration. [Image: see text]

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