Liver‐Inspired Polyetherketoneketone Scaffolds Simulate Regenerative Signals and Mobilize Anti‐Inflammatory Reserves to Reprogram Macrophage Metabolism for Boosted Osteoporotic Osseointegration (Adv. Sci. 25/2023)

Liver‐Inspired Polyetherketoneketone Scaffolds In article number 2302136, Hao Gu, Jin Wen, Xinquan Jiang, and co‐workers are inspired from the liver extracellular skeleton morphology and develop a biomimetic scaffold. The scaffold reproduces an identical bio‐signal derived from the bio‐template in m...

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Autores principales: Gu, Hao, Zhu, Yuhui, Yang, Jiawei, Jiang, Ruixue, Deng, Yuwei, Li, Anshuo, Fang, Yingjing, Wu, Qianju, Tu, Honghuan, Chang, Haishuang, Wen, Jin, Jiang, Xinquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Cover Picture
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477849/
http://dx.doi.org/10.1002/advs.202370166
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author Gu, Hao
Zhu, Yuhui
Yang, Jiawei
Jiang, Ruixue
Deng, Yuwei
Li, Anshuo
Fang, Yingjing
Wu, Qianju
Tu, Honghuan
Chang, Haishuang
Wen, Jin
Jiang, Xinquan
author_facet Gu, Hao
Zhu, Yuhui
Yang, Jiawei
Jiang, Ruixue
Deng, Yuwei
Li, Anshuo
Fang, Yingjing
Wu, Qianju
Tu, Honghuan
Chang, Haishuang
Wen, Jin
Jiang, Xinquan
author_sort Gu, Hao
collection PubMed
description Liver‐Inspired Polyetherketoneketone Scaffolds In article number 2302136, Hao Gu, Jin Wen, Xinquan Jiang, and co‐workers are inspired from the liver extracellular skeleton morphology and develop a biomimetic scaffold. The scaffold reproduces an identical bio‐signal derived from the bio‐template in macrophages and causes retrograde translocation of arginase‐2 in mitochondria, optimizing osseointegration. [Image: see text]
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spelling pubmed-104778492023-09-06 Liver‐Inspired Polyetherketoneketone Scaffolds Simulate Regenerative Signals and Mobilize Anti‐Inflammatory Reserves to Reprogram Macrophage Metabolism for Boosted Osteoporotic Osseointegration (Adv. Sci. 25/2023) Gu, Hao Zhu, Yuhui Yang, Jiawei Jiang, Ruixue Deng, Yuwei Li, Anshuo Fang, Yingjing Wu, Qianju Tu, Honghuan Chang, Haishuang Wen, Jin Jiang, Xinquan Adv Sci (Weinh) Cover Picture Liver‐Inspired Polyetherketoneketone Scaffolds In article number 2302136, Hao Gu, Jin Wen, Xinquan Jiang, and co‐workers are inspired from the liver extracellular skeleton morphology and develop a biomimetic scaffold. The scaffold reproduces an identical bio‐signal derived from the bio‐template in macrophages and causes retrograde translocation of arginase‐2 in mitochondria, optimizing osseointegration. [Image: see text] John Wiley and Sons Inc. 2023-09-05 /pmc/articles/PMC10477849/ http://dx.doi.org/10.1002/advs.202370166 Text en © 2023 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Cover Picture
Gu, Hao
Zhu, Yuhui
Yang, Jiawei
Jiang, Ruixue
Deng, Yuwei
Li, Anshuo
Fang, Yingjing
Wu, Qianju
Tu, Honghuan
Chang, Haishuang
Wen, Jin
Jiang, Xinquan
Liver‐Inspired Polyetherketoneketone Scaffolds Simulate Regenerative Signals and Mobilize Anti‐Inflammatory Reserves to Reprogram Macrophage Metabolism for Boosted Osteoporotic Osseointegration (Adv. Sci. 25/2023)
title Liver‐Inspired Polyetherketoneketone Scaffolds Simulate Regenerative Signals and Mobilize Anti‐Inflammatory Reserves to Reprogram Macrophage Metabolism for Boosted Osteoporotic Osseointegration (Adv. Sci. 25/2023)
title_full Liver‐Inspired Polyetherketoneketone Scaffolds Simulate Regenerative Signals and Mobilize Anti‐Inflammatory Reserves to Reprogram Macrophage Metabolism for Boosted Osteoporotic Osseointegration (Adv. Sci. 25/2023)
title_fullStr Liver‐Inspired Polyetherketoneketone Scaffolds Simulate Regenerative Signals and Mobilize Anti‐Inflammatory Reserves to Reprogram Macrophage Metabolism for Boosted Osteoporotic Osseointegration (Adv. Sci. 25/2023)
title_full_unstemmed Liver‐Inspired Polyetherketoneketone Scaffolds Simulate Regenerative Signals and Mobilize Anti‐Inflammatory Reserves to Reprogram Macrophage Metabolism for Boosted Osteoporotic Osseointegration (Adv. Sci. 25/2023)
title_short Liver‐Inspired Polyetherketoneketone Scaffolds Simulate Regenerative Signals and Mobilize Anti‐Inflammatory Reserves to Reprogram Macrophage Metabolism for Boosted Osteoporotic Osseointegration (Adv. Sci. 25/2023)
title_sort liver‐inspired polyetherketoneketone scaffolds simulate regenerative signals and mobilize anti‐inflammatory reserves to reprogram macrophage metabolism for boosted osteoporotic osseointegration (adv. sci. 25/2023)
topic Cover Picture
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477849/
http://dx.doi.org/10.1002/advs.202370166
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