Inhibition of CDK1 Overcomes Oxaliplatin Resistance by Regulating ACSL4‐mediated Ferroptosis in Colorectal Cancer

Oxaliplatin is a widely used chemotherapy drug for patients with advanced colorectal cancer (CRC); however, frequent drug resistance limits its therapeutic efficacy in patients. Here, this work identifies cyclin‐dependent kinase 1 (CDK1) as a critical contributor to oxaliplatin resistance via in vit...

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Detalles Bibliográficos
Autores principales: Zeng, Kaixuan, Li, Weihao, Wang, Yue, Zhang, Zifei, Zhang, Linjie, Zhang, Weili, Xing, Yue, Zhou, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477855/
https://www.ncbi.nlm.nih.gov/pubmed/37428466
http://dx.doi.org/10.1002/advs.202301088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477855/
https://www.ncbi.nlm.nih.gov/pubmed/37428466
http://dx.doi.org/10.1002/advs.202301088

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