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Inhibition of CDK1 Overcomes Oxaliplatin Resistance by Regulating ACSL4‐mediated Ferroptosis in Colorectal Cancer
Oxaliplatin is a widely used chemotherapy drug for patients with advanced colorectal cancer (CRC); however, frequent drug resistance limits its therapeutic efficacy in patients. Here, this work identifies cyclin‐dependent kinase 1 (CDK1) as a critical contributor to oxaliplatin resistance via in vit...
Autores principales: | Zeng, Kaixuan, Li, Weihao, Wang, Yue, Zhang, Zifei, Zhang, Linjie, Zhang, Weili, Xing, Yue, Zhou, Chi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477855/ https://www.ncbi.nlm.nih.gov/pubmed/37428466 http://dx.doi.org/10.1002/advs.202301088 |
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