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Fungal COP9 signalosome assembly requires connection of two trimeric intermediates for integration of intrinsic deneddylase

The conserved eight-subunit COP9 signalosome (CSN) is required for multicellular fungal development. The CSN deneddylase cooperates with the Cand1 exchange factor to control replacements of E3 ubiquitin cullin RING ligase receptors, providing specificity to eukaryotic protein degradation. Aspergillu...

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Detalles Bibliográficos
Autores principales:	Bakti, Fruzsina, Stupperich, Helena, Schmitt, Kerstin, Valerius, Oliver, Köhler, Anna M., Meister, Cindy, Strohdiek, Anja, Harting, Rebekka, Sasse, Christoph, Heimel, Kai, Neumann, Piotr, Ficner, Ralf, Braus, Gerhard H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477865/ https://www.ncbi.nlm.nih.gov/pubmed/37603767 http://dx.doi.org/10.1073/pnas.2305049120

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