Yin Yang 1‐Induced Long Noncoding RNA DUXAP9 Drives the Progression of Oral Squamous Cell Carcinoma by Blocking CDK1‐Mediated EZH2 Degradation (Adv. Sci. 25/2023)

Yin Yang 1‐Induced Long Noncoding RNA DUXAP9 A nuclear‐localized lncRNA DUXAP9 blocking CDK1‐mediated EZH2 phosphorylation and inhibiting EZH2 translocation from the nucleus to the cytoplasm, and thereby averting EZH2 degradation, suggesting that DUXAP9 may be a potential target for OSCC therapy. Mo...

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Detalles Bibliográficos
Autores principales: Zhou, Wenkai, Feng, Yisheng, Lin, Chengzhong, CHAO, Chi Kuan, He, Ziqi, Zhao, Shiyao, Xue, Jieyuan, Zhao, Xu‐Yun, Cao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Frontispiece
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477866/
http://dx.doi.org/10.1002/advs.202370169
Descripción
Sumario:Yin Yang 1‐Induced Long Noncoding RNA DUXAP9 A nuclear‐localized lncRNA DUXAP9 blocking CDK1‐mediated EZH2 phosphorylation and inhibiting EZH2 translocation from the nucleus to the cytoplasm, and thereby averting EZH2 degradation, suggesting that DUXAP9 may be a potential target for OSCC therapy. More details can be found in article number 2207549 by Xu‐Yun Zhao, Wei Cao, and co‐workers. [Image: see text]

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