Cargando…

LncRNA ARGI Contributes to Virus‐Induced Pancreatic β Cell Inflammation Through Transcriptional Activation of IFN‐Stimulated Genes

Type 1 diabetes (T1D) is a complex autoimmune disease that develops in genetically susceptible individuals. Most T1D‐associated single nucleotide polymorphisms (SNPs) are located in non‐coding regions of the human genome. Interestingly, SNPs in long non‐coding RNAs (lncRNAs) may result in the disrup...

Descripción completa

Detalles Bibliográficos
Autores principales:	González‐Moro, Itziar, Garcia‐Etxebarria, Koldo, Mendoza, Luis Manuel, Fernández‐Jiménez, Nora, Mentxaka, Jon, Olazagoitia‐Garmendia, Ane, Arroyo, María Nicol, Sawatani, Toshiaki, Moreno‐Castro, Cristina, Vinci, Chiara, Op de Beek, Anne, Cnop, Miriam, Igoillo‐Esteve, Mariana, Santin, Izortze
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477904/ https://www.ncbi.nlm.nih.gov/pubmed/37382191 http://dx.doi.org/10.1002/advs.202300063

Ejemplares similares

Implication of m6A mRNA Methylation in Susceptibility to Inflammatory Bowel Disease
por: Sebastian-delaCruz, Maialen, et al.
Publicado: (2020)

The Role of lncRNAs in Gene Expression Regulation through mRNA Stabilization
por: Sebastian-delaCruz, Maialen, et al.
Publicado: (2021)

MAGI2 Gene Region and Celiac Disease
por: Jauregi-Miguel, Amaia, et al.
Publicado: (2019)

A novel RT-QPCR-based assay for the relative quantification of residue specific m6A RNA methylation
por: Castellanos-Rubio, Ainara, et al.
Publicado: (2019)

A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells
por: González-Moro, Itziar, et al.
Publicado: (2023)

tRNA Biology in the Pathogenesis of Diabetes: Role of Genetic and Environmental Factors
por: Arroyo, Maria Nicol, et al.
Publicado: (2021)

An unusual burn caused by hot argy wormwood leaf water
por: Liang, Xun, et al.
Publicado: (2011)

Host Genetics and Microbiota Interactions in Colorectal Cancer: Shared or Independent Risk?
por: Romero-Garmendia, Irati, et al.
Publicado: (2022)

From Omic Layers to Personalized Medicine in Colorectal Cancer: The Road Ahead
por: Romero-Garmendia, Irati, et al.
Publicado: (2023)

Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells
por: Cnop, Miriam, et al.
Publicado: (2017)

Transcription Factor Binding Site Enrichment Analysis in Co-Expression Modules in Celiac Disease
por: Romero-Garmendia, Irati, et al.
Publicado: (2018)

The Aswan Rheumatic heart disease reGIstry: rationale and preliminary results of the ARGI database
por: Kotit, Susy, et al.
Publicado: (2023)

In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo
por: Fantuzzi, Federica, et al.
Publicado: (2022)

The Argi system: one-step purification of proteins tagged with arginine-rich cell-penetrating peptides
por: Bartnicki, Filip, et al.
Publicado: (2017)

The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines
por: Eizirik, Décio L., et al.
Publicado: (2012)

Functional evolutionary convergence of long noncoding RNAs involved in embryonic development
por: Olazagoitia-Garmendia, Ane, et al.
Publicado: (2023)

Performance of the Use of Genetic Information to Assess the Risk of Colorectal Cancer in the Basque Population
por: Garcia-Etxebarria, Koldo, et al.
Publicado: (2022)

Extraction of Natural Dye from Aerial Parts of Argy Wormwood Based on Optimized Taguchi Approach and Functional Finishing of Cotton Fabric
por: Shafiq, Faizan, et al.
Publicado: (2021)

Genetic Variants as Predictors of the Success of Colorectal Cancer Treatments
por: Garcia-Etxebarria, Koldo, et al.
Publicado: (2023)

GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models
por: Gorgogietas, Vyron, et al.
Publicado: (2023)

Towards a Functional Cure for Diabetes Using Stem Cell-Derived Beta Cells: Are We There Yet?
por: Bourgeois, Stephanie, et al.
Publicado: (2021)

From urban planning and emergency training to Pokémon Go: applications of virtual reality GIS (VRGIS) and augmented reality GIS (ARGIS) in personal, public and environmental health
por: Kamel Boulos, Maged N., et al.
Publicado: (2017)

Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB
por: Cunha, Daniel A., et al.
Publicado: (2009)

Evolutionary history of bovine endogenous retroviruses in the Bovidae family
por: Garcia-Etxebarria, Koldo, et al.
Publicado: (2013)

Erbb4 Is Required for Cerebellar Development and Malignant Phenotype of Medulloblastoma
por: Aldaregia, Juncal, et al.
Publicado: (2020)

Mining the transcriptome of target tissues of autoimmune and degenerative pancreatic β-cell and brain diseases to discover therapies
por: Yi, Xiaoyan, et al.
Publicado: (2022)

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon-γ–Induced Pancreatic β-Cell Apoptosis
por: Moore, Fabrice, et al.
Publicado: (2009)

Ubiquitin Fold Modifier 1 (UFM1) and Its Target UFBP1 Protect Pancreatic Beta Cells from ER Stress-Induced Apoptosis
por: Lemaire, Katleen, et al.
Publicado: (2011)

Consistency of metagenomic assignment programs in simulated and real data
por: Garcia-Etxebarria, Koldo, et al.
Publicado: (2014)

Endogenous Retroviruses in Domestic Animals
por: Garcia-Etxebarria, Koldo, et al.
Publicado: (2014)

Human Papillomavirus (HPV) genotype 18 variants in patients with clinical manifestations of HPV related infections in Bilbao, Spain
por: Arroyo, Sara L, et al.
Publicado: (2012)

Glucose-6-Phosphate Dehydrogenase of Trypanosomatids: Characterization, Target Validation, and Drug Discovery
por: Gupta, Shreedhara, et al.
Publicado: (2011)

Current Drug Repurposing Strategies for Rare Neurodegenerative Disorders
por: Shah, Sweta, et al.
Publicado: (2021)

A New Method for Extracting Skin Microbes Allows Metagenomic Analysis of Whole-Deep Skin
por: Garcia-Garcerà, Marc, et al.
Publicado: (2013)

Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity
por: Lytrivi, Maria, et al.
Publicado: (2020)

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic β-Cell Apoptosis via Regulation of the BH3-Only Protein Bim
por: Santin, Izortze, et al.
Publicado: (2011)

The Transcription Factor C/EBP delta Has Anti-Apoptotic and Anti-Inflammatory Roles in Pancreatic Beta Cells
por: Moore, Fabrice, et al.
Publicado: (2012)

Infective endocarditis in a patient with metastatic colorectal cancer
por: Callejo-Goena, Almudena, et al.
Publicado: (2018)

A functional genomic approach to identify reference genes for human pancreatic beta cell real-time quantitative RT-PCR analysis
por: Alvelos, Maria Inês, et al.
Publicado: (2021)

Highly Reproducible Hyperthermia Response in Water, Agar, and Cellular Environment by Discretely PEGylated Magnetite Nanoparticles
por: Castellanos-Rubio, Idoia, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_bk1rlepnved4n8edkrvdae161u