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Integration of single-cell RNA sequencing and bulk RNA transcriptome sequencing reveals a heterogeneous immune landscape and pivotal cell subpopulations associated with colorectal cancer prognosis

INTRODUCTION: Colorectal cancer (CRC) is a highly heterogeneous cancer. The molecular and cellular characteristics differ between the colon and rectal cancer type due to the differences in their anatomical location and pathological properties. With the advent of single-cell sequencing, it has become...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Liu, Yang, Wang, Xinyu, Zhang, Cheng, Hou, Mingxiao, Liu, Yunen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477986/
https://www.ncbi.nlm.nih.gov/pubmed/37675100
http://dx.doi.org/10.3389/fimmu.2023.1184167