Cargando…

Integration of single-cell RNA sequencing and bulk RNA transcriptome sequencing reveals a heterogeneous immune landscape and pivotal cell subpopulations associated with colorectal cancer prognosis

INTRODUCTION: Colorectal cancer (CRC) is a highly heterogeneous cancer. The molecular and cellular characteristics differ between the colon and rectal cancer type due to the differences in their anatomical location and pathological properties. With the advent of single-cell sequencing, it has become...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Qian, Liu, Yang, Wang, Xinyu, Zhang, Cheng, Hou, Mingxiao, Liu, Yunen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10477986/ https://www.ncbi.nlm.nih.gov/pubmed/37675100 http://dx.doi.org/10.3389/fimmu.2023.1184167

Ejemplares similares

Single-Cell and Bulk RNA Sequencing Reveal Malignant Epithelial Cell Heterogeneity and Prognosis Signatures in Gastric Carcinoma
por: Huang, Zhihong, et al.
Publicado: (2022)

Integration of bulk RNA sequencing data and single-cell RNA sequencing analysis on the heterogeneity in patients with colorectal cancer
por: Zhang, Jiawei, et al.
Publicado: (2023)

Integration of Bulk RNA Sequencing and Single-Cell RNA Sequencing to Reveal Uveal Melanoma Tumor Heterogeneity and Cells Related to Survival
por: Gao, Guohong, et al.
Publicado: (2022)

T-cell exhaustion signatures characterize the immune landscape and predict HCC prognosis via integrating single-cell RNA-seq and bulk RNA-sequencing
por: Chi, Hao, et al.
Publicado: (2023)

Concordance of MERFISH spatial transcriptomics with bulk and single-cell RNA sequencing
por: Liu, Jonathan, et al.
Publicado: (2022)

Single-cell RNA-sequencing analyses identify heterogeneity of CD8(+) T cell subpopulations and novel therapy targets in melanoma
por: Deng, Weiwei, et al.
Publicado: (2020)

Integrating Bulk Transcriptome and Single-Cell RNA Sequencing Data Reveals the Landscape of the Immune Microenvironment in Thoracic Aortic Aneurysms
por: Wang, Qunhui, et al.
Publicado: (2022)

Integrative analysis of single-cell and bulk RNA sequencing unveils the senescence landscape in ischemic stroke
por: Fu, Longhui, et al.
Publicado: (2023)

Landscape of Immune Cells Heterogeneity in Liver Transplantation by Single-Cell RNA Sequencing Analysis
por: Li, Xinqiang, et al.
Publicado: (2022)

Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data
por: Sun, Duanchen, et al.
Publicado: (2022)

Integrating single-cell and bulk RNA sequencing to predict prognosis and immunotherapy response in prostate cancer
por: Wen, Xiao Yan, et al.
Publicado: (2023)

Reference Transcriptomes of Porcine Peripheral Immune Cells Created Through Bulk and Single-Cell RNA Sequencing
por: Herrera-Uribe, Juber, et al.
Publicado: (2021)

Peripheral immune cell death in sepsis based on bulk RNA and single-cell RNA sequencing
por: Liu, Shanshou, et al.
Publicado: (2023)

Single-cell sequencing and bulk RNA sequencing reveal a cell differentiation-related multigene panel to predict the prognosis and immunotherapy response of hepatocellular carcinoma
por: Liu, Jifeng, et al.
Publicado: (2023)

Integrating scRNA and bulk-RNA sequencing develops a cell senescence signature for analyzing tumor heterogeneity in clear cell renal cell carcinoma
por: Gong, Qiming, et al.
Publicado: (2023)

From bulk, single-cell to spatial RNA sequencing
por: Li, Xinmin, et al.
Publicado: (2021)

Single-cell and bulk RNA sequencing reveal cancer-associated fibroblast heterogeneity and a prognostic signature in prostate cancer
por: Liu, Wen, et al.
Publicado: (2023)

Integrating bulk and single‐cell RNA sequencing reveals cellular heterogeneity and immune infiltration in hepatocellular carcinoma
por: Wang, Tingjie, et al.
Publicado: (2022)

Single-Cell RNA Sequencing With Combined Use of Bulk RNA Sequencing to Reveal Cell Heterogeneity and Molecular Changes at Acute Stage of Ischemic Stroke in Mouse Cortex Penumbra Area
por: Guo, Kang, et al.
Publicado: (2021)

Identification and validation of a novel cuproptosis-related stemness signature to predict prognosis and immune landscape in lung adenocarcinoma by integrating single-cell and bulk RNA-sequencing
por: Yang, Jia, et al.
Publicado: (2023)

Integrated single-cell and bulk RNA sequencing analysis identified pyroptosis-related signature for diagnosis and prognosis in osteoarthritis
por: Chen, Yanzhong, et al.
Publicado: (2023)

Identification of the immune-associated characteristics and predictive biomarkers of keratoconus based on single-cell RNA-sequencing and bulk RNA-sequencing
por: Niu, Xiaoguang, et al.
Publicado: (2023)

Collaborating single-cell and bulk RNA sequencing for comprehensive characterization of the intratumor heterogeneity and prognostic model development for bladder cancer
por: Wang, Jie, et al.
Publicado: (2023)

Integration of Single-Cell RNA Sequencing and Bulk RNA Sequencing Reveals That TAM2-Driven Genes Affect Immunotherapeutic Response and Prognosis in Pancreatic Cancer
por: Du, Yan, et al.
Publicado: (2023)

CAF signature predicts the prognosis of colorectal cancer patients: A retrospective study based on bulk RNA sequencing and single-cell RNA sequencing data
por: Liang, Chen, et al.
Publicado: (2023)

Single-cell and bulk RNA sequencing reveals Anoikis related genes to guide prognosis and immunotherapy in osteosarcoma
por: Zhong, Cheng, et al.
Publicado: (2023)

A novel necroptosis-related gene signature for predict prognosis of glioma based on single-cell and bulk RNA sequencing
por: Guo, Kai, et al.
Publicado: (2022)

Integration of single-cell RNA sequencing and spatial transcriptomics to reveal the glioblastoma heterogeneity
por: Perdyan, Adrian, et al.
Publicado: (2023)

Integrating bulk and single-cell sequencing reveals the phenotype-associated cell subpopulations in sepsis-induced acute lung injury
por: Wang, Fuquan, et al.
Publicado: (2022)

Integration of Single-Cell RNA Sequencing and Bulk RNA Sequencing Data to Establish and Validate a Prognostic Model for Patients With Lung Adenocarcinoma
por: Jiang, Aimin, et al.
Publicado: (2022)

Landscape of cell heterogeneity and evolutionary trajectory in ulcerative colitis-associated colon cancer revealed by single-cell RNA sequencing
por: Wang, Quan, et al.
Publicado: (2021)

Transcriptomic landscape of breast cancers through mRNA sequencing
por: Eswaran, Jeyanthy, et al.
Publicado: (2012)

The heterogeneous immune landscape between lung adenocarcinoma and squamous carcinoma revealed by single-cell RNA sequencing
por: Wang, Chengdi, et al.
Publicado: (2022)

Single-Cell RNA Sequencing Reveals Endothelial Cell Transcriptome Heterogeneity Under Homeostatic Laminar Flow
por: Liu, Ziqing, et al.
Publicado: (2021)

Integrated analysis of single-cell and bulk RNA-sequencing reveals tumor heterogeneity and a signature based on NK cell marker genes for predicting prognosis in hepatocellular carcinoma
por: Li, Shuo, et al.
Publicado: (2023)

Single-Cell RNA Sequencing Reveals Distinct Cardiac-Derived Stromal Cell Subpopulations
por: Hoffman, Jessica R., et al.
Publicado: (2022)

Single-cell and bulk RNA sequencing identifies T cell marker genes score to predict the prognosis of pancreatic ductal adenocarcinoma
por: Zheng, Haoran, et al.
Publicado: (2023)

Dissecting the cellular landscape and transcriptome network in viral myocarditis by single-cell RNA sequencing
por: Lasrado, Ninaad, et al.
Publicado: (2022)

Single-Cell RNA Sequencing of Human Corpus Cavernosum Reveals Cellular Heterogeneity Landscapes in Erectile Dysfunction
por: Fang, Dong, et al.
Publicado: (2022)

Elaboration and validation of a prognostic signature associated with disulfidoptosis in lung adenocarcinoma, consolidated with integration of single-cell RNA sequencing and bulk RNA sequencing techniques
por: He, Dabao, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_jaqr6cj6274o34lfeqg1v9snik