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Total network controllability analysis discovers explainable drugs for Covid-19 treatment
BACKGROUND: The active pursuit of network medicine for drug repurposing, particularly for combating Covid-19, has stimulated interest in the concept of structural controllability in cellular networks. We sought to extend this theory, focusing on the defense rather than control of the cell against vi...
Autores principales: | Wei, Xinru, Pan, Chunyu, Zhang, Xizhe, Zhang, Weixiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478273/ https://www.ncbi.nlm.nih.gov/pubmed/37670359 http://dx.doi.org/10.1186/s13062-023-00410-9 |
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