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Total network controllability analysis discovers explainable drugs for Covid-19 treatment

BACKGROUND: The active pursuit of network medicine for drug repurposing, particularly for combating Covid-19, has stimulated interest in the concept of structural controllability in cellular networks. We sought to extend this theory, focusing on the defense rather than control of the cell against vi...

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Detalles Bibliográficos
Autores principales: Wei, Xinru, Pan, Chunyu, Zhang, Xizhe, Zhang, Weixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478273/
https://www.ncbi.nlm.nih.gov/pubmed/37670359
http://dx.doi.org/10.1186/s13062-023-00410-9

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