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Disease progression model anchored around clinical diagnosis in longitudinal cohorts: example of Alzheimer’s disease and related dementia

BACKGROUND: Alzheimer’s disease and related dementia (ADRD) are characterized by multiple and progressive anatomo-clinical changes including accumulation of abnormal proteins in the brain, brain atrophy and severe cognitive impairment. Understanding the sequence and timing of these changes is of pri...

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Detalles Bibliográficos
Autores principales: Lespinasse, Jérémie, Dufouil, Carole, Proust-Lima, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478286/
https://www.ncbi.nlm.nih.gov/pubmed/37670234
http://dx.doi.org/10.1186/s12874-023-02009-0

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