Cargando…

SEC23A confers ER stress resistance in gastric cancer by forming the ER stress-SEC23A-autophagy negative feedback loop

BACKGROUND: Sec23 homolog A (SEC23A), a core component of coat protein complex II (COPII), has been reported to be involved in several cancers. However, the role of SEC23A in gastric cancer remains unclear. METHODS: The expression of SEC23A in gastric cancer was analyzed by using qRT-PCR, western bl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Quan, Liu, Kanghui, Xiao, Jian, Shen, Kuan, Wang, Yuanhang, Zhou, Xinyi, Wang, Jiawei, Xu, Zekuan, Yang, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478313/ https://www.ncbi.nlm.nih.gov/pubmed/37670384 http://dx.doi.org/10.1186/s13046-023-02807-w

Ejemplares similares

ULK1 phosphorylates Sec23A and mediates autophagy-induced inhibition of ER-to-Golgi traffic
por: Gan, Wenjia, et al.
Publicado: (2017)

Sec12 Binds to Sec16 at Transitional ER Sites
por: Montegna, Elisabeth A., et al.
Publicado: (2012)

The Functional Role of SEC23 in Vesicle Transportation, Autophagy and Cancer
por: Jing, Jingchen, et al.
Publicado: (2019)

SEC23A rescues SEC23B-deficient congenital dyserythropoietic anemia type II
por: King, Richard, et al.
Publicado: (2021)

Sec23a inhibits the self-renewal of melanoma cancer stem cells via inactivation of ER-phagy
por: Sun, Zhiwei, et al.
Publicado: (2022)

CREB3L2-mediated expression of Sec23A/Sec24D is involved in hepatic stellate cell activation through ER-Golgi transport
por: Tomoishi, Shotaro, et al.
Publicado: (2017)

The novel ER stress inducer Sec C triggers apoptosis by sulfating ER cysteine residues and degrading YAP via ER stress in pancreatic cancer cells
por: Wang, Junxia, et al.
Publicado: (2022)

Pancreatic SEC23B deficiency is sufficient to explain the perinatal lethality of germline SEC23B deficiency in mice
por: Khoriaty, Rami, et al.
Publicado: (2016)

Identification of Cysteine Ubiquitylation Sites on the Sec23A Protein of the COPII Complex Required for Vesicle Formation from the ER
por: Amodio, Giuseppina, et al.
Publicado: (2017)

Sec16 function in ER export and autophagy is independent of its phosphorylation in Saccharomyces cerevisiae
por: Yorimitsu, Tomohiro, et al.
Publicado: (2020)

The ULK1-FBXW5-SEC23B nexus controls autophagy
por: Jeong, Yeon-Tae, et al.
Publicado: (2018)

Sar1 Interacts with Sec23/Sec24 and Sec13/Sec31 Complexes: Insight into Its Involvement in the Assembly of Coat Protein Complex II in the Microsporidian Nosema bombycis
por: Sun, Fuzhen, et al.
Publicado: (2022)

The Arabidopsis COPII components, AtSEC23A and AtSEC23D, are essential for pollen wall development and exine patterning
por: Aboulela, Mostafa, et al.
Publicado: (2018)

Bi‐allelic mutation in SEC16B alters collagen trafficking and increases ER stress
por: El‐Gazzar, Ahmed, et al.
Publicado: (2023)

N-acetylation and phosphorylation of Sec complex subunits in the ER membrane
por: Soromani, Christina, et al.
Publicado: (2012)

ALG-2 Attenuates COPII Budding In Vitro and Stabilizes the Sec23/Sec31A Complex
por: la Cour, Jonas M., et al.
Publicado: (2013)

ERAD and protein import defects in a sec61 mutant lacking ER-lumenal loop 7
por: Tretter, Thomas, et al.
Publicado: (2013)

Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23p
Publicado: (1995)

Non-canonical role of wild-type SEC23B in the cellular stress response pathway
por: Yehia, Lamis, et al.
Publicado: (2021)

CK2 Phosphorylates Sec31 and Regulates ER-To-Golgi Trafficking
por: Koreishi, Mayuko, et al.
Publicado: (2013)

p125A exists as part of the mammalian Sec13/Sec31 COPII subcomplex to facilitate ER-Golgi transport
por: Ong, Yan Shan, et al.
Publicado: (2010)

Sequential interactions with Sec23 control the direction of vesicle traffic
por: Lord, Christopher, et al.
Publicado: (2011)

Stress-induced phase separation of ERES components into Sec bodies precedes ER exit inhibition in mammalian cells
por: van Leeuwen, Wessel, et al.
Publicado: (2022)

Cancer associated mutations in Sec61γ alter the permeability of the ER translocase
por: Witham, Christopher M., et al.
Publicado: (2021)

Smy2p Participates in COPII Vesicle Formation Through the Interaction with Sec23p/Sec24p Subcomplex
por: Higashio, Hironori, et al.
Publicado: (2008)

S100A8 transported by SEC23A inhibits metastatic colonization via autocrine activation of autophagy
por: Sun, Zhiwei, et al.
Publicado: (2020)

MoSec61β, the beta subunit of Sec61, is involved in fungal development and pathogenicity, plant immunity, and ER-phagy in Magnaporthe oryzae
por: Wei, Yun-Yun, et al.
Publicado: (2020)

Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins
por: Scott, Daniel C., et al.
Publicado: (2008)

Concentrative ER export of the serotonin transporter relies exclusively on an interaction with Sec24C
por: Sucic, Sonja, et al.
Publicado: (2010)

Evolutionary Gain of Function for the ER Membrane Protein Sec62 from Yeast to Humans
por: Müller, Linda, et al.
Publicado: (2010)

Sec16 influences transitional ER sites by regulating rather than organizing COPII
por: Bharucha, Nike, et al.
Publicado: (2013)

Sec20 Is Required for Autophagic and Endocytic Degradation Independent of Golgi-ER Retrograde Transport
por: Lakatos, Zsolt, et al.
Publicado: (2019)

AtSec62 is critical for plant development and is involved in ER‐phagy in Arabidopsis thaliana
por: Hu, Shuai, et al.
Publicado: (2019)

Chaperone-Mediated Sec61 Channel Gating during ER Import of Small Precursor Proteins Overcomes Sec61 Inhibitor-Reinforced Energy Barrier
por: Haßdenteufel, Sarah, et al.
Publicado: (2018)

Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylation
por: Barbieri, Guido, et al.
Publicado: (2023)

Correction to: S100A8 transported by SEC23A inhibits metastatic colonization via autocrine activation of autophagy
por: Sun, Zhiwei, et al.
Publicado: (2022)

MicroRNA-375/SEC23A as biomarkers of the in vitro efficacy of vandetanib
por: Lassalle, Sandra, et al.
Publicado: (2016)

SEC23B is required for pancreatic acinar cell function in adult mice
por: Khoriaty, Rami, et al.
Publicado: (2017)

SEC23A Is an Independent Prognostic Biomarker in Bladder Cancer Correlated With MAPK Signaling
por: Zeng, Bin, et al.
Publicado: (2021)

Let’s talk about Secs: Sec61, Sec62 and Sec63 in signal transduction, oncology and personalized medicine
por: Linxweiler, Maximilian, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ae1coklog54moridtjssh79d6g