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Perilipin 5 deficiency aggravates cardiac hypertrophy by stimulating lactate production in leptin-deficient mice
BACKGROUND: Perilipin 5 (Plin5) is well known to maintain the stability of intracellular lipid droplets (LDs) and regulate fatty acid metabolism in oxidative tissues. It is highly expressed in the heart, but its roles have yet to be fully elucidated. METHODS: Plin5-deficient mice and Plin5/leptin-do...
Autores principales: | Jian, Lele, Gao, Xing, Wang, Chao, Sun, Xiao, Xu, Yuqiao, Han, Ruili, Wang, Yuying, Xu, Shenhui, Ding, Lan, Zhou, Jingjun, Gu, Yu, Zhao, Yuanlin, Yang, Ying, Yuan, Yuan, Ye, Jing, Zhang, Lijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478499/ https://www.ncbi.nlm.nih.gov/pubmed/37667357 http://dx.doi.org/10.1186/s13062-023-00411-8 |
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