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Perilipin 5 deficiency aggravates cardiac hypertrophy by stimulating lactate production in leptin-deficient mice

BACKGROUND: Perilipin 5 (Plin5) is well known to maintain the stability of intracellular lipid droplets (LDs) and regulate fatty acid metabolism in oxidative tissues. It is highly expressed in the heart, but its roles have yet to be fully elucidated. METHODS: Plin5-deficient mice and Plin5/leptin-do...

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Detalles Bibliográficos
Autores principales: Jian, Lele, Gao, Xing, Wang, Chao, Sun, Xiao, Xu, Yuqiao, Han, Ruili, Wang, Yuying, Xu, Shenhui, Ding, Lan, Zhou, Jingjun, Gu, Yu, Zhao, Yuanlin, Yang, Ying, Yuan, Yuan, Ye, Jing, Zhang, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478499/
https://www.ncbi.nlm.nih.gov/pubmed/37667357
http://dx.doi.org/10.1186/s13062-023-00411-8

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