Structure and function relationship of formate de­hydrogenases: an overview of recent progress

Formate de­hydrogenases (FDHs) catalyze the two-electron oxidation of formate to carbon dioxide. FDHs can be divided into several groups depending on their subunit composition and active-site metal ions. Metal-dependent (Mo- or W-containing) FDHs from prokaryotic organisms belong to the superfamily...

Descripción completa

Detalles Bibliográficos
Autores principales: Kobayashi, Ami, Taketa, Midori, Sowa, Keisei, Kano, Kenji, Higuchi, Yoshiki, Ogata, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Topical Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478512/
https://www.ncbi.nlm.nih.gov/pubmed/37668215
http://dx.doi.org/10.1107/S2052252523006437
Descripción
Sumario:Formate de­hydrogenases (FDHs) catalyze the two-electron oxidation of formate to carbon dioxide. FDHs can be divided into several groups depending on their subunit composition and active-site metal ions. Metal-dependent (Mo- or W-containing) FDHs from prokaryotic organisms belong to the superfamily of molybdenum enzymes and are members of the di­methyl­sulfoxide reductase family. In this short review, recent progress in the structural analysis of FDHs together with their potential biotechnological applications are summarized.

Ejemplares similares