Cargando…
LifeSoaks: a tool for analyzing solvent channels in protein crystals and obstacles for soaking experiments
Due to the structural complexity of proteins, their corresponding crystal arrangements generally contain a significant amount of solvent-occupied space. These areas allow a certain degree of intracrystalline protein flexibility and mobility of solutes. Therefore, knowledge of the geometry of solvent...
Autores principales: | Pletzer-Zelgert, Jonathan, Ehrt, Christiane, Fender, Inken, Griewel, Axel, Flachsenberg, Florian, Klebe, Gerhard, Rarey, Matthias |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478636/ https://www.ncbi.nlm.nih.gov/pubmed/37561404 http://dx.doi.org/10.1107/S205979832300582X |
Ejemplares similares
-
Spatiotemporal development of soaked protein crystal
por: Mizutani, Ryuta, et al.
Publicado: (2014) -
Two Methods, One Goal: Structural Differences between Cocrystallization and Crystal Soaking to Discover Ligand Binding Poses
por: Wienen‐Schmidt, Barbara, et al.
Publicado: (2020) -
Soaking up stress
por: Tuma, Rabiya S.
Publicado: (2006) -
Gentle, fast and effective crystal soaking by acoustic dispensing
por: Collins, Patrick M., et al.
Publicado: (2017) -
Exiting the tunnel of uncertainty: crystal soak to validated hit
por: Martin, Mathew P., et al.
Publicado: (2022)