Implementation of targeted next-generation sequencing for the diagnosis of drug-resistant tuberculosis in low-resource settings: a programmatic model, challenges, and initial outcomes

Targeted next-generation sequencing (tNGS) from clinical specimens has the potential to become a comprehensive tool for routine drug-resistance (DR) prediction of Mycobacterium tuberculosis complex strains (MTBC), the causative agent of tuberculosis (TB). However, TB mainly affects low- and middle-i...

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Detalles Bibliográficos
Autores principales: de Araujo, Leonardo, Cabibbe, Andrea Maurizio, Mhuulu, Lusia, Ruswa, Nunurai, Dreyer, Viola, Diergaardt, Azaria, Günther, Gunar, Claassens, Mareli, Gerlach, Christiane, Utpatel, Christian, Cirillo, Daniela Maria, Nepolo, Emmanuel, Niemann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Public Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478709/
https://www.ncbi.nlm.nih.gov/pubmed/37674674
http://dx.doi.org/10.3389/fpubh.2023.1204064

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