Evaluating the expression of heat shock protein 27 and topoisomerase II α in a retrospective cohort of patients diagnosed with locally advanced breast cancer and treated with neoadjuvant anthracycline-based chemotherapies

BACKGROUND: Neoadjuvant anthracycline-based chemotherapy (NAC) is a major regimen for the treatment of local advanced breast cancer (LABC), while resistance to NAC remains a paramount clinical obstacle. To investigate the role of heat shock protein 27 (Hsp27) and/or topoisomerase IIα (TopoIIα) in LA...

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Detalles Bibliográficos
Autores principales: Zhuang, Yixuan, Zhang, Fan, Xu, Yue, He, Lifang, Huang, Wenhe, Hong, Chaoqun, Cui, Yukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478710/
https://www.ncbi.nlm.nih.gov/pubmed/37675221
http://dx.doi.org/10.3389/fonc.2023.1067179

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