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CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression

AIMS: Haploinsufficiency of the chromo-domain protein CHD7 underlies most cases of CHARGE syndrome, a multisystem birth defect including congenital heart malformation. Context specific roles for CHD7 in various stem, progenitor, and differentiated cell lineages have been reported. Previously, we sho...

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Detalles Bibliográficos
Autores principales:	Stathopoulou, Athanasia, Wang, Ping, Thellier, Charlotte, Kelly, Robert G, Zheng, Deyou, Scambler, Peter J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478754/ https://www.ncbi.nlm.nih.gov/pubmed/37052590 http://dx.doi.org/10.1093/cvr/cvad059

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