Aripriprazole induced severe oculogyric dystonia treated with electroconvulsive therapy(ECT)

INTRODUCTION: Aripiprazole is the third generation Antipsychotic, and Dopamine serotonin system stabiliser.It is partial agonist at D2 and 5 HT1 A and antagonist at 5 HT2.Most commonly seen adverse effects are Akathesia, fatugue,insomnia and headache the major advanatage is less propensity for extrapyramidal side effects and lmetabolic side eefects. OBJECTIVES: To report a case of Schizophrenia treated with Aripiprazole 15mg/day developiing occular gyric crisis which was tratment resistant. METHODS: We administered Electroconvulsvive therapy, bidirectional brief pulse constant current 8 ECTS, under General anesthesia with medical fitness . RESULTS: Patient Showed complete resolution of Dystonia after second ECTs and Showed improvment in Pyschosis Parameterd. Assessment using Naranjo Protocol made. CONCLUSIONS: Electroconvulsive therapy therapy is viable alternative to manage Dystonia when medical treatment fails DISCLOSURE OF INTEREST: None Declared