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Dysregulated Arginine Metabolism Is Linked to Retinal Degeneration in Cep250 Knockout Mice

PURPOSE: Degeneration of retinal photoreceptors is frequently observed in diverse ciliopathy disorders, and photoreceptor cilium gates the molecular trafficking between the inner and the outer segment (OS). This study aims to generate a homozygous global Cep250 knockout (KO) mouse and study the resu...

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Detalles Bibliográficos
Autores principales:	Xiang, Lue, Yang, Qiao-Li, Xie, Bin-Tao, Zeng, Hui-Yi, Ding, Liu-Jun, Rao, Feng-Qin, Yan, Tong, Lu, Fan, Chen, Qi, Huang, Xiu-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479211/ https://www.ncbi.nlm.nih.gov/pubmed/37656476 http://dx.doi.org/10.1167/iovs.64.12.2

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