Pharmacokinetics of Orbital Topotecan After Ophthalmic Artery Chemosurgery and Intravenous Infusion in the Swine Model

PURPOSE: Surgery, multiagent systemic chemotherapy, and radiation are used for patients with orbital retinoblastoma but are associated with unacceptable short- and long-term toxicity (including death). We studied orbital and systemic exposure of topotecan in the swine model after ophthalmic artery c...

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Detalles Bibliográficos
Autores principales: Requejo, Flavio, Opezzo, Javier, Vater, Alan, Asprea, Marcelo, Lagomarsino, Eduardo, Sampor, Claudia, Fandiño, Adriana, Chantada, Guillermo, Francis, Jasmine H., Abramson, David H., Schaiquevich, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479255/
https://www.ncbi.nlm.nih.gov/pubmed/37656475
http://dx.doi.org/10.1167/iovs.64.12.3

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