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TNFR1/p38αMAPK signaling in Nex+ supraspinal neurons regulates sex-specific chronic neuropathic pain

Upregulation of soluble tumor necrosis factor (sTNF) cytokine signaling through TNF receptor 1 (TNFR1) and subsequent neuronal hyperexcitability are observed in both animal models and human chronic neuropathic pain (CNP) [1–4]. To test the hypothesis that supraspinal circuitry is critical to pain ch...

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Detalles Bibliográficos
Autores principales:	Swanson, Kathryn A., Nguyen, Kayla L., Gupta, Shruti, Ricard, Jerome, Bethea, John R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479400/ https://www.ncbi.nlm.nih.gov/pubmed/37674712 http://dx.doi.org/10.21203/rs.3.rs-3273237/v1

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