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Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia

INTRODUCTION: Long-term schizophrenia, even in remission, is necessarily accompanied by residual symptoms that may be quite pronounced and may significantly affect many aspects of the patient’s life, requiring exploration of specific therapeutic approaches. The alleviation of residual symptoms is an...

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Autores principales: Mitikhin, V., Kuzminova, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479478/
http://dx.doi.org/10.1192/j.eurpsy.2023.2319
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author Mitikhin, V.
Kuzminova, M.
author_facet Mitikhin, V.
Kuzminova, M.
author_sort Mitikhin, V.
collection PubMed
description INTRODUCTION: Long-term schizophrenia, even in remission, is necessarily accompanied by residual symptoms that may be quite pronounced and may significantly affect many aspects of the patient’s life, requiring exploration of specific therapeutic approaches. The alleviation of residual symptoms is an important factor in the patient’s better adjustment. OBJECTIVES: Assessment and study clinical characteristics long-term schizophrenia. METHODS: Clinical, statistical, psychometric. A total of 90 patients, mean age 66,6±13,3 years, 26 males, 64 females were examined. RESULTS: Negative symptoms were predominant in patients with long-term schizophrenia (17,8±6,7). It was represented by: abstract thinking disorders (2,8±1,0), stereotyped thinking (2,7±1,1), passive-apathetic social isolation (2,6±1,2), avolition (2,6±0,8), flattening of affect (2,5±0,8). It manifested as lack of expressiveness in facial expressions and gestures, deficit of communicative gestures as well as emotional indifference (2,4±1,1), limitation of contacts with people, and spontaneous and fluent speech impairments. Positive symptoms were rare, mainly represented by suspiciousness (2,2±1,2), sometimes rising to delirium (1,8±1,4). Conceptual disorganization was detected in 1,9±0,7. Agitation and aggression were generally not characteristic of those surveyed. Depression/anxiety was quite pronounced in patients with long-term schizophrenia. Depression (1,8±0,8) was represented by low mood, hopelessness and loss of social interests. Anxiety (2,9±1,2) was even more prominent and predominant amongst all symptoms. CONCLUSIONS: The authors expanded our understanding of the clinical characteristics of residual symptoms of long-term schizophrenia to allow timely identification and provision of medical and rehabilitative care. DISCLOSURE OF INTEREST: None Declared
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spelling pubmed-104794782023-09-06 Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia Mitikhin, V. Kuzminova, M. Eur Psychiatry Abstract INTRODUCTION: Long-term schizophrenia, even in remission, is necessarily accompanied by residual symptoms that may be quite pronounced and may significantly affect many aspects of the patient’s life, requiring exploration of specific therapeutic approaches. The alleviation of residual symptoms is an important factor in the patient’s better adjustment. OBJECTIVES: Assessment and study clinical characteristics long-term schizophrenia. METHODS: Clinical, statistical, psychometric. A total of 90 patients, mean age 66,6±13,3 years, 26 males, 64 females were examined. RESULTS: Negative symptoms were predominant in patients with long-term schizophrenia (17,8±6,7). It was represented by: abstract thinking disorders (2,8±1,0), stereotyped thinking (2,7±1,1), passive-apathetic social isolation (2,6±1,2), avolition (2,6±0,8), flattening of affect (2,5±0,8). It manifested as lack of expressiveness in facial expressions and gestures, deficit of communicative gestures as well as emotional indifference (2,4±1,1), limitation of contacts with people, and spontaneous and fluent speech impairments. Positive symptoms were rare, mainly represented by suspiciousness (2,2±1,2), sometimes rising to delirium (1,8±1,4). Conceptual disorganization was detected in 1,9±0,7. Agitation and aggression were generally not characteristic of those surveyed. Depression/anxiety was quite pronounced in patients with long-term schizophrenia. Depression (1,8±0,8) was represented by low mood, hopelessness and loss of social interests. Anxiety (2,9±1,2) was even more prominent and predominant amongst all symptoms. CONCLUSIONS: The authors expanded our understanding of the clinical characteristics of residual symptoms of long-term schizophrenia to allow timely identification and provision of medical and rehabilitative care. DISCLOSURE OF INTEREST: None Declared Cambridge University Press 2023-07-19 /pmc/articles/PMC10479478/ http://dx.doi.org/10.1192/j.eurpsy.2023.2319 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Mitikhin, V.
Kuzminova, M.
Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia
title Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia
title_full Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia
title_fullStr Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia
title_full_unstemmed Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia
title_short Clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia
title_sort clinico-psychopathological characteristics of patients with residual states in long-term schizophrenia
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479478/
http://dx.doi.org/10.1192/j.eurpsy.2023.2319
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