CHCHD2 Thr61Ile mutation impairs F1F0-ATPase assembly in in vitro and in vivo models of Parkinson’s disease

Mitochondrial dysfunction is a significant pathological alteration that occurs in Parkinson’s disease (PD), and the Thr61Ile (T61I) mutation in coiled-coil helix coiled-coil helix domain containing 2 (CHCHD2), a crucial mitochondrial protein, has been reported to cause Parkinson’s disease. F1F0-ATPa...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xiang, Lin, Yuwan, Zhang, Zhiling, Tang, Yuting, Ye, Panghai, Dai, Wei, Zhang, Wenlong, Liu, Hanqun, Peng, Guoyou, Huang, Shuxuan, Qiu, Jiewen, Guo, Wenyuan, Zhu, Xiaoqin, Wu, Zhuohua, Kuang, Yaoyun, Xu, Pingyi, Zhou, Miaomiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10479855/
https://www.ncbi.nlm.nih.gov/pubmed/37488867
http://dx.doi.org/10.4103/1673-5374.378010

Ejemplares similares

Ejemplares similares