Tricky sepsis biomarker: Extremely high procalcitonin in squamous cell lung cancer with doubtful infection

Procalcitonin is a 116 amino acid polypeptide synthesized by the C‐cells of the thyroid gland. Elevated serum procalcitonin levels are generally thought to be the result of systemic bacterial infection, but recent reviews have suggested an association between procalcitonin and patients with cancer....

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Autores principales: Ermayanti, Sabrina, Afriani, Afriani, Firdaus, Dimas Bayu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2023
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480142/
https://www.ncbi.nlm.nih.gov/pubmed/37681067
http://dx.doi.org/10.1002/rcr2.1210
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author Ermayanti, Sabrina
Afriani, Afriani
Firdaus, Dimas Bayu
author_facet Ermayanti, Sabrina
Afriani, Afriani
Firdaus, Dimas Bayu
author_sort Ermayanti, Sabrina
collection PubMed
description Procalcitonin is a 116 amino acid polypeptide synthesized by the C‐cells of the thyroid gland. Elevated serum procalcitonin levels are generally thought to be the result of systemic bacterial infection, but recent reviews have suggested an association between procalcitonin and patients with cancer. This case report discusses an illustrative case with elevated procalcitonin levels in a patient with squamous cell carcinoma and multiple metastases. The increase in procalcitonin in patients may be due to an inflammatory state in the tumour microenvironment. Elevated procalcitonin is associated with disease progression, the presence of metastases, and a poor prognosis.
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spelling pubmed-104801422023-09-07 Tricky sepsis biomarker: Extremely high procalcitonin in squamous cell lung cancer with doubtful infection Ermayanti, Sabrina Afriani, Afriani Firdaus, Dimas Bayu Respirol Case Rep Case Reports Procalcitonin is a 116 amino acid polypeptide synthesized by the C‐cells of the thyroid gland. Elevated serum procalcitonin levels are generally thought to be the result of systemic bacterial infection, but recent reviews have suggested an association between procalcitonin and patients with cancer. This case report discusses an illustrative case with elevated procalcitonin levels in a patient with squamous cell carcinoma and multiple metastases. The increase in procalcitonin in patients may be due to an inflammatory state in the tumour microenvironment. Elevated procalcitonin is associated with disease progression, the presence of metastases, and a poor prognosis. John Wiley & Sons, Ltd 2023-09-05 /pmc/articles/PMC10480142/ /pubmed/37681067 http://dx.doi.org/10.1002/rcr2.1210 Text en © 2023 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Ermayanti, Sabrina
Afriani, Afriani
Firdaus, Dimas Bayu
Tricky sepsis biomarker: Extremely high procalcitonin in squamous cell lung cancer with doubtful infection
title Tricky sepsis biomarker: Extremely high procalcitonin in squamous cell lung cancer with doubtful infection
title_full Tricky sepsis biomarker: Extremely high procalcitonin in squamous cell lung cancer with doubtful infection
title_fullStr Tricky sepsis biomarker: Extremely high procalcitonin in squamous cell lung cancer with doubtful infection
title_full_unstemmed Tricky sepsis biomarker: Extremely high procalcitonin in squamous cell lung cancer with doubtful infection
title_short Tricky sepsis biomarker: Extremely high procalcitonin in squamous cell lung cancer with doubtful infection
title_sort tricky sepsis biomarker: extremely high procalcitonin in squamous cell lung cancer with doubtful infection
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480142/
https://www.ncbi.nlm.nih.gov/pubmed/37681067
http://dx.doi.org/10.1002/rcr2.1210
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AT firdausdimasbayu trickysepsisbiomarkerextremelyhighprocalcitonininsquamouscelllungcancerwithdoubtfulinfection

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