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CRISPR imaging reveals chromatin fluctuation at the centromere region related to cellular senescence
The human genome is spatially and temporally organized in the nucleus as chromatin, and the dynamic structure of chromatin is closely related to genome functions. Cellular senescence characterized by an irreversible arrest of proliferation is accompanied by chromatin reorganisation in the nucleus du...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480159/ https://www.ncbi.nlm.nih.gov/pubmed/37670098 http://dx.doi.org/10.1038/s41598-023-41770-6 |