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The COMPASS subunit Spp1 protects nascent DNA at the Tus/Ter replication fork barrier by limiting DNA availability to nucleases

Homologous recombination factors play a crucial role in protecting nascent DNA during DNA replication, but the role of chromatin in this process is largely unknown. Here, we used the bacterial Tus/Ter barrier known to induce a site-specific replication fork stalling in S. cerevisiae. We report that...

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Detalles Bibliográficos
Autores principales: Ghaddar, Nagham, Corda, Yves, Luciano, Pierre, Galli, Martina, Doksani, Ylli, Géli, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480214/
https://www.ncbi.nlm.nih.gov/pubmed/37669924
http://dx.doi.org/10.1038/s41467-023-41100-4