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Recent advances in targeting the “undruggable” proteins: from drug discovery to clinical trials
Undruggable proteins are a class of proteins that are often characterized by large, complex structures or functions that are difficult to interfere with using conventional drug design strategies. Targeting such undruggable targets has been considered also a great opportunity for treatment of human d...
Autores principales: | Xie, Xin, Yu, Tingting, Li, Xiang, Zhang, Nan, Foster, Leonard J., Peng, Cheng, Huang, Wei, He, Gu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480221/ https://www.ncbi.nlm.nih.gov/pubmed/37669923 http://dx.doi.org/10.1038/s41392-023-01589-z |
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