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The shelf life of ASDs: 2. Predicting the shelf life at storage conditions
Amorphous solid dispersions (ASDs) are a widely used formulation technology for poorly water-soluble active pharmaceutical ingredients (API). Depending on the API-polymer combination and API load in the ASD, the amorphous API might be thermodynamically metastable and crystallize over time. The cryst...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480311/ https://www.ncbi.nlm.nih.gov/pubmed/37680879 http://dx.doi.org/10.1016/j.ijpx.2023.100207 |