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Involvement of Nrf2, JAK and COX pathways in acetaminophen-induced nephropathy: Role of some antioxidants

OBJECTIVES: Acetaminophen (APAP)-induced nephrotoxicity is detrimental consequence for which there has not been a standardized therapeutic regimen. Although, N-acetylcysteine (NAC) is a well-known antidote used in APAP-induced hepatotoxicity, its benefit in nephrotoxicity caused by APAP is almost la...

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Detalles Bibliográficos
Autores principales: Alqahtani, Qamraa H., Fadda, Laila M., Alhusaini, Ahlam M., Hasan, Iman H., Ali, Hanaa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480313/
https://www.ncbi.nlm.nih.gov/pubmed/37680754
http://dx.doi.org/10.1016/j.jsps.2023.101752

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