Linezolid toxic optic neuropathy: A case report and review of visual prognosis

PURPOSE: To describe a case of linezolid toxic optic neuropathy in a 71-year-old female and review the relevant literature. OBSERVATIONS: An adult female with progressive, symmetric vision loss was hypothesized to have linezolid toxic optic neuropathy. Following cessation of linezolid, the patient e...

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Autores principales: Toolan, Kevin J., Fondriest, Jacob, Keenan, Kaitlin, Mizen, Thomas, Stosic, Milena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480323/
https://www.ncbi.nlm.nih.gov/pubmed/37680308
http://dx.doi.org/10.1016/j.ajoc.2023.101922
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author Toolan, Kevin J.
Fondriest, Jacob
Keenan, Kaitlin
Mizen, Thomas
Stosic, Milena
author_facet Toolan, Kevin J.
Fondriest, Jacob
Keenan, Kaitlin
Mizen, Thomas
Stosic, Milena
author_sort Toolan, Kevin J.
collection PubMed
description PURPOSE: To describe a case of linezolid toxic optic neuropathy in a 71-year-old female and review the relevant literature. OBSERVATIONS: An adult female with progressive, symmetric vision loss was hypothesized to have linezolid toxic optic neuropathy. Following cessation of linezolid, the patient experienced improvement in visual function over two months. CONCLUSIONS AND IMPORTANCE: Patients diagnosed with linezolid toxic optic neuropathy can expect some return of visual function after cessation. The degree of return does not correlate to the cumulative dose of the drug. The goal of this study was to summarize and add to the current body of literature on the topic.
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spelling pubmed-104803232023-09-07 Linezolid toxic optic neuropathy: A case report and review of visual prognosis Toolan, Kevin J. Fondriest, Jacob Keenan, Kaitlin Mizen, Thomas Stosic, Milena Am J Ophthalmol Case Rep Case Report PURPOSE: To describe a case of linezolid toxic optic neuropathy in a 71-year-old female and review the relevant literature. OBSERVATIONS: An adult female with progressive, symmetric vision loss was hypothesized to have linezolid toxic optic neuropathy. Following cessation of linezolid, the patient experienced improvement in visual function over two months. CONCLUSIONS AND IMPORTANCE: Patients diagnosed with linezolid toxic optic neuropathy can expect some return of visual function after cessation. The degree of return does not correlate to the cumulative dose of the drug. The goal of this study was to summarize and add to the current body of literature on the topic. Elsevier 2023-08-26 /pmc/articles/PMC10480323/ /pubmed/37680308 http://dx.doi.org/10.1016/j.ajoc.2023.101922 Text en © 2023 The Authors. Published by Elsevier Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Toolan, Kevin J.
Fondriest, Jacob
Keenan, Kaitlin
Mizen, Thomas
Stosic, Milena
Linezolid toxic optic neuropathy: A case report and review of visual prognosis
title Linezolid toxic optic neuropathy: A case report and review of visual prognosis
title_full Linezolid toxic optic neuropathy: A case report and review of visual prognosis
title_fullStr Linezolid toxic optic neuropathy: A case report and review of visual prognosis
title_full_unstemmed Linezolid toxic optic neuropathy: A case report and review of visual prognosis
title_short Linezolid toxic optic neuropathy: A case report and review of visual prognosis
title_sort linezolid toxic optic neuropathy: a case report and review of visual prognosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480323/
https://www.ncbi.nlm.nih.gov/pubmed/37680308
http://dx.doi.org/10.1016/j.ajoc.2023.101922
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