Cargando…

Evaluating cancer cell line and patient‐derived xenograft recapitulation of tumor and non‐diseased tissue gene expression profiles in silico

Mostrar otras versiones (1)

BACKGROUND: Preclinical models like cancer cell lines and patient‐derived xenografts (PDXs) are vital for studying disease mechanisms and evaluating treatment options. It is essential that they accurately recapitulate the disease state of interest to generate results that will translate in the clini...

Descripción completa

Detalles Bibliográficos
Autores principales:	Williams, Avery S., Wilk, Elizabeth J., Fisher, Jennifer L., Lasseigne, Brittany N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480419/ https://www.ncbi.nlm.nih.gov/pubmed/37533331 http://dx.doi.org/10.1002/cnr2.1874

Ejemplares similares

Evaluating cancer cell line and patient-derived xenograft recapitulation of tumor and non-diseased tissue gene expression profiles in silico
por: Williams, Avery S., et al.
Publicado: (2023)

Patient‐derived xenograft mouse models of pseudomyxoma peritonei recapitulate the human inflammatory tumor microenvironment
por: Kuracha, Murali R., et al.
Publicado: (2016)

Establishment of 6 pediatric rhabdomyosarcoma patient’s derived xenograft models closely recapitulating patients’ tumor characteristics
por: Gasparini, Patrizia, et al.
Publicado: (2022)

A Novel Cell Line Based Orthotopic Xenograft Mouse Model That Recapitulates Human Hepatoblastoma
por: Woodfield, Sarah E., et al.
Publicado: (2017)

Xenografts derived from patients with head and neck cancer recapitulate patient tumour properties
por: Makita, Haruna, et al.
Publicado: (2021)

Recapitulation of prostate tissue cell type-specific transcriptomes by an in vivo primary prostate tissue xenograft model
por: Gross, Nelson T., et al.
Publicado: (2020)

Considerations and challenges for sex-aware drug repurposing
por: Fisher, Jennifer L., et al.
Publicado: (2022)

Preclinical transgenic and patient‐derived xenograft models recapitulate the radiological features of human adamantinomatous craniopharyngioma
por: Boult, Jessica K. R., et al.
Publicado: (2017)

The landscape of SETBP1 gene expression and transcription factor activity across human tissues
por: Whitlock, Jordan H., et al.
Publicado: (2023)

Patient-Derived Xenografts and Organoids Recapitulate Castration-Resistant Prostate Cancer with Sustained Androgen Receptor Signaling
por: Van Hemelryk, Annelies, et al.
Publicado: (2022)

Human pancreatic cancer xenografts recapitulate key aspects of cancer cachexia
por: Delitto, Daniel, et al.
Publicado: (2016)

Promising xenograft animal model recapitulating the features of human pancreatic cancer
por: Miao, Jin-Xin, et al.
Publicado: (2020)

Humanized Patient-derived Xenograft Models of Disseminated Ovarian Cancer Recapitulate Key Aspects of the Tumor Immune Environment within the Peritoneal Cavity
por: Steinkamp, Mara P., et al.
Publicado: (2023)

A role for GLUT3 in glioblastoma cell invasion that is not recapitulated by GLUT1
por: Libby, Catherine J, et al.
Publicado: (2021)

Serial patient-derived orthotopic xenografting of adenoid cystic carcinomas recapitulates stable expression of phenotypic alterations and innervation
por: Cornett, Ashley, et al.
Publicado: (2019)

Heterogeneity Analysis of Esophageal Squamous Cell Carcinoma in Cell Lines, Tumor Tissues and Patient-Derived Xenografts
por: Ma, Fayang, et al.
Publicado: (2021)

Establishment of Novel Gastric Cancer Patient-Derived Xenografts and Cell Lines: Pathological Comparison between Primary Tumor, Patient-Derived, and Cell-Line Derived Xenografts
por: Kuwata, Takeshi, et al.
Publicado: (2019)

Comparison of Proteomics Profiles Between Xenografts Derived from Cell Lines and Primary Tumors of Thyroid Carcinoma
por: Fang, Luo, et al.
Publicado: (2021)

Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease
por: Chernova, T, et al.
Publicado: (2016)

Automatic Optimization of an in Silico Model of Human iPSC Derived Cardiomyocytes Recapitulating Calcium Handling Abnormalities
por: Paci, Michelangelo, et al.
Publicado: (2018)

Human Patient-Derived Brain Tumor Models to Recapitulate Ependymoma Tumor Vasculature
por: Tang-Schomer, Min D., et al.
Publicado: (2023)

Recapitulating the Size and Cargo of Tumor Exosomes in a Tissue-Engineered Model
por: Villasante, Aranzazu, et al.
Publicado: (2016)

Patient-derived pancreatic cancer-on-a-chip recapitulates the tumor microenvironment
por: Haque, Muhammad R., et al.
Publicado: (2022)

Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse
por: Clappier, Emmanuelle, et al.
Publicado: (2011)

A novel patient-derived intra-femoral xenograft model of bone metastatic prostate cancer that recapitulates mixed osteolytic and osteoblastic lesions
por: Raheem, Omer, et al.
Publicado: (2011)

Intraductal patient‐derived xenografts of estrogen receptor α‐positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions
por: Fiche, Maryse, et al.
Publicado: (2018)

Spontaneous mouse lymphoma in patient-derived tumor xenografts: The importance of systematic analysis of xenografted human tumor tissues in preclinical efficacy trials
por: Chateau-Joubert, Sophie, et al.
Publicado: (2021)

3D patient-derived tumor models to recapitulate pediatric brain tumors In Vitro
por: Tang-Schomer, Min D., et al.
Publicado: (2022)

DNA and RNA Sequencing Recapitulated Aberrant Tumor Metabolism in Liver Cancer Cell Lines
por: Sun, Yihong, et al.
Publicado: (2021)

Ex vivo treatment of prostate tumor tissue recapitulates in vivo therapy response
por: Zhang, Wenhao, et al.
Publicado: (2018)

CINmetrics: an R package for analyzing copy number aberrations as a measure of chromosomal instability
por: Oza, Vishal H., et al.
Publicado: (2023)

Nucleic acid liquid biopsies in Alzheimer's disease: current state, challenges, and opportunities
por: Soelter, Tabea M., et al.
Publicado: (2022)

Liquid biopsies in epilepsy: biomarkers for etiology, diagnosis, prognosis, and therapeutics
por: Whitlock, Jordan H., et al.
Publicado: (2021)

Recapitulation
Publicado: (1866)

Hypoxia-regulated gene expression explains differences between melanoma cell line-derived xenografts and patient-derived xenografts
por: Bhadury, Joydeep, et al.
Publicado: (2016)

3D spheroid culturing of Astyanax mexicanus liver-derived cell lines recapitulates distinct transcriptomic and metabolic states of in vivo tissue environment
por: Biswas, Tathagata, et al.
Publicado: (2023)

A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors
por: Costa, Barbara, et al.
Publicado: (2021)

Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico
por: Broom, Aron, et al.
Publicado: (2020)

Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity
por: Sarvestani, Samaneh K., et al.
Publicado: (2021)

Outgrowth of erlotinib-resistant subpopulations recapitulated in patient-derived lung tumor spheroids and organoids
por: Banda, Malathi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sj276l85kerkt2crj4tfgf8r43