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Effects of adult education on cognitive function and risk of dementia in older adults: a longitudinal analysis

INTRODUCTION: Mid/late-life cognitive activities are associated with a lower rate of subsequent cognitive decline and lower subsequent dementia risk over time. METHODS: In this study, we investigated the association between adult education class participation and subsequent cognitive decline and dem...

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Autores principales: Takeuchi, Hikaru, Kawashima, Ryuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480502/
https://www.ncbi.nlm.nih.gov/pubmed/37680542
http://dx.doi.org/10.3389/fnagi.2023.1212623
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author Takeuchi, Hikaru
Kawashima, Ryuta
author_facet Takeuchi, Hikaru
Kawashima, Ryuta
author_sort Takeuchi, Hikaru
collection PubMed
description INTRODUCTION: Mid/late-life cognitive activities are associated with a lower rate of subsequent cognitive decline and lower subsequent dementia risk over time. METHODS: In this study, we investigated the association between adult education class participation and subsequent cognitive decline and dementia risk over time after adjusting for baseline cognitive function and genetic risk of dementia, correcting for several potential confounding variables, using a large prospective cohort data of participants from the UK Biobank study followed from 2006 to 2010. RESULTS: The results revealed that participation in adult education classes at baseline was associated with greater subsequent retention of fluid intelligence score. Cox proportional hazard models revealed that subjects who participated in adult education classes showed a significantly lower risk of incident dementia 5 years after baseline compared with those that did not at baseline. DISCUSSION: In this study, we show that participation in adult education classes preceded greater retention of subsequent fluid intelligence and a lower risk of developing dementia after 5 years: this association did not change after adjusting for cognitive function at baseline or genetic predisposition to dementia. Accordingly, participation in such classes could reduce the risk of developing dementia.
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spelling pubmed-104805022023-09-07 Effects of adult education on cognitive function and risk of dementia in older adults: a longitudinal analysis Takeuchi, Hikaru Kawashima, Ryuta Front Aging Neurosci Neuroscience INTRODUCTION: Mid/late-life cognitive activities are associated with a lower rate of subsequent cognitive decline and lower subsequent dementia risk over time. METHODS: In this study, we investigated the association between adult education class participation and subsequent cognitive decline and dementia risk over time after adjusting for baseline cognitive function and genetic risk of dementia, correcting for several potential confounding variables, using a large prospective cohort data of participants from the UK Biobank study followed from 2006 to 2010. RESULTS: The results revealed that participation in adult education classes at baseline was associated with greater subsequent retention of fluid intelligence score. Cox proportional hazard models revealed that subjects who participated in adult education classes showed a significantly lower risk of incident dementia 5 years after baseline compared with those that did not at baseline. DISCUSSION: In this study, we show that participation in adult education classes preceded greater retention of subsequent fluid intelligence and a lower risk of developing dementia after 5 years: this association did not change after adjusting for cognitive function at baseline or genetic predisposition to dementia. Accordingly, participation in such classes could reduce the risk of developing dementia. Frontiers Media S.A. 2023-08-23 /pmc/articles/PMC10480502/ /pubmed/37680542 http://dx.doi.org/10.3389/fnagi.2023.1212623 Text en Copyright © 2023 Takeuchi and Kawashima. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Takeuchi, Hikaru
Kawashima, Ryuta
Effects of adult education on cognitive function and risk of dementia in older adults: a longitudinal analysis
title Effects of adult education on cognitive function and risk of dementia in older adults: a longitudinal analysis
title_full Effects of adult education on cognitive function and risk of dementia in older adults: a longitudinal analysis
title_fullStr Effects of adult education on cognitive function and risk of dementia in older adults: a longitudinal analysis
title_full_unstemmed Effects of adult education on cognitive function and risk of dementia in older adults: a longitudinal analysis
title_short Effects of adult education on cognitive function and risk of dementia in older adults: a longitudinal analysis
title_sort effects of adult education on cognitive function and risk of dementia in older adults: a longitudinal analysis
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480502/
https://www.ncbi.nlm.nih.gov/pubmed/37680542
http://dx.doi.org/10.3389/fnagi.2023.1212623
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