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Current progress in genomics and targeted therapies for neurofibromatosis type 2

Neurofibromatosis type 2 (NF2), a multiple neoplasia syndrome, is a manifestation of an impaired expression of the merlin protein, exerting inhibitory effects on cell proliferation signals due to abnormalities of the NF2 gene located on chromosome 22. About half of patients inherit a germline mutati...

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Detalles Bibliográficos
Autores principales:	Hiruta, Ryo, Saito, Kiyoshi, Bakhit, Mudathir, Fujii, Masazumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Fukushima Society of Medical Science 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480513/ https://www.ncbi.nlm.nih.gov/pubmed/37468280 http://dx.doi.org/10.5387/fms.2023-05

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