Mini-PE, a prime editor with compact Cas9 and truncated reverse transcriptase

Prime editor (PE) is a versatile genome editing tool that does not need extra DNA donors or inducing double-strand breaks. However, in vivo implementation of PE remains a challenge because of its oversized composition. In this study, we screened out the smallest truncated Moloney murine leukemia vir...

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Detalles Bibliográficos
Autores principales: Lan, Ting, Chen, Huangyao, Tang, Chengcheng, Wei, Yuhui, Liu, Yang, Zhou, Jizeng, Zhuang, Zhenpeng, Zhang, Quanjun, Chen, Min, Zhou, Xiaoqing, Chi, Yue, Wang, Jinling, He, Yu, Lai, Liangxue, Zou, Qingjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480570/
https://www.ncbi.nlm.nih.gov/pubmed/37680986
http://dx.doi.org/10.1016/j.omtn.2023.08.018

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