Novel hybrid motifs of 4-nitroimidazole-piperazinyl tagged 1,2,3-triazoles: Synthesis, crystal structure, anticancer evaluations, and molecular docking study

4-((4-(1-benzyl-2-methyl-4-nitro-1H-imidazole-5-yl)piperazine-1-yl)methyl)-1-substituted-1H-1,2,3-triazole motifs are designed and synthesized via click chemistry. The reaction of 1-(N(1)-benzyl- 2-methyl-4-nitro-1H-imidazole- 5-yl)-4-(prop-2-yn-1-yl) piperazine 5 as new scaffold with diverse primar...

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Detalles Bibliográficos
Autores principales: Saber, SadeekahO.W., Al-Qawasmeh, Raed A., Abu-Qatouseh, Luay, Shtaiwi, Amneh, Khanfar, Monther A., Al-Soud, Yaseen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480608/
https://www.ncbi.nlm.nih.gov/pubmed/37681149
http://dx.doi.org/10.1016/j.heliyon.2023.e19327

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